Isophysalin G

• Description:

  Isophysalin G is a steroid that inhibits NO production induced by Lipopolysaccharides (HY-D1056) in macrophages with an IC50 of 64.01 μM[1].

• UNSPSC:

  12352005

• Target:

  Others

• Type:

  Natural Products

• Related Pathways:

  Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/isophysalin-g.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@]12[C@]34[C@]5([H])[C@]6([C@@](C(O[C@]2([H])C6)=O)([H])CO[C@](C5=O)([C@@]7([H])[C@]([C@@]8(C(C=C7)=C[C@H](CC8=O)O)C)([H])CC[C@@]4(C(O1)=O)O)O3)C

• Molecular Formula:

  C28H30O10

• Molecular Weight:

  526.53

• References & Citations:

  [1]Qiu L, et al. Steroids and flavonoids from Physalis alkekengi var. franchetii and their inhibitory effects on nitric oxide production. J Nat Prod. 2008 Apr;71 (4) :642-6.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [152221-21-1]