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DRAK2-IN-1

CAT: 0804-HY-122629-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-122629-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DRAK2-IN-1, compound 16, is a potent, selective and ATP-competitive DRAK2 inhibitor with IC50and Kivalues of 3 nM and 0.26 nM, respectively. DRAK2-IN-1 also has inbitory effect on DRAK1 (IC50=51 nM) [1].
CAS Number
871837-60-4
UNSPSC
12352005
Target
DAPK
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/drak2-in-1.html
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCCCC(NC1=CC2=C(NC(/C2=C3NC4=C(C=CC=C4)C\3=N\O)=O)C=C1)=O
Molecular Formula
C21H20N4O3
Molecular Weight
376.41
References & Citations
[1]Jung ME, et al.Discovery of indirubin derivatives as new class of DRAK2 inhibitors from high throughput screening.Bioorg Med Chem Lett. 2016 Jun 1;26 (11) :2719-23
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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