DRAK2

CAT: 0209-101-M593Size: 50 µgDry Ice: NoHazardous: No

1 / 1

CAT#:0209-101-M593Size:50 µg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

STK17B (also known as DRAK2) is a member of the serine/threonine kinase family and is related to death-associated protein kinase that triggers apoptosis. STK17B is selectively important for T-cell survival and inhibition of STK17B has therapeutic potential for autoimmune disease. T-cell survival depends on a balance of T-cell receptor and co-stimulatory signals and deficiency of STK17B can affect autoimmune disease susceptibility without generalized suppression of the immune system.

Synonyms

Serine/threonine-protein kinase 17B, DAP kinase-related apoptosis-inducing protein kinase 2

NCBI Gene ID

9262

UniProt

O94768

Accession Number

NP_004217.1

Accession Number mRNA

NM_004226.3

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human DRAK2

Clone

(#4U29)

Applications

Purification Method

Protein G chromatography

Assay Protocol

Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

Host or Source

Mouse

Isotype

IgG2

UniProtKB · O94768

Serine/threonine-protein kinase 17B

ST17B_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: O94768
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: STK17B
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 2.7.11.1
Processing: —
Secondary accessions: —

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Apoptosis

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneMembraneNucleus

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

PTM

Phosphoprotein

Alternative Products

Catalog	Name
71225	DRAK2
HY-122629-01	DRAK2-IN-1
2149P	DRAK2 Peptide
GWB-75A265	DRAK2, Antibody
343012-01	DRAK2 discontinued
GTR17697883	DRAK2 Antibody
MBS3606334-01	DRAK2-IN-16