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Morusin

CAT: 0804-HY-N0622-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0622-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Morusin is a prenylated flavonoid isolated from Morus alba Linn. with various biological activities, such as antitumor, antioxidant, and anti-bacteria property. Morusin could inhibit NF-κB and STAT3 activity.
CAS Number
62596-29-6
Product Name Alternative
Mulberrochromene
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; NF-κB; STAT
Type
Natural Products
Related Pathways
Anti-infection; JAK/STAT Signaling; NF-κB; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Morusin.html
Concentration
10mM
Purity
99.94
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C1C2=C(O)C=C3C(C=CC(C)(C)O3)=C2OC(C4=CC=C(O)C=C4O)=C1C/C=C(C)\C
Molecular Formula
C25H24O6
Molecular Weight
420.45
Precautions
H302, H315, H319, H335
References & Citations
[1]Li H, et al. Morusin suppresses breast cancer cell growth in vitro and in vivo through C/EBPβ and PPARγ mediated lipoapoptosis. J Exp Clin Cancer Res. 2015 Nov 4;34:137.|[2]Lee JC, et al. Morusin induces apoptosis and suppresses NF-kappaB activity in human colorectal cancer HT-29 cells. Biochem Biophys Res Commun. 2008 Jul 18;372 (1) :236-42.|[3]Lim SL, et al. Morusin induces cell death through inactivating STAT3 signaling in prostate cancer cells. Am J Cancer Res. 2014 Dec 15;5 (1) :289-99.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
RelA/p65; STAT3

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