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Cimetidine sulfoxide

CAT: 0804-HY-136338-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-136338-01Size:5 mg
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Description
Cimetidine sulfoxide (Cimetidine sulphoxide) is a sulfoxide metabolite of Cimetidine. Cimetidine is a histamine H2-receptor antagonist. Cimetidine has the potential for peptic ulcer disease and upper gastrointestinal haemorrhage treatment[1].
CAS Number
54237-72-8
Product Name Alternative
Cimetidine sulphoxide
UNSPSC
12352005
Hazard Statement
H301, H311, H331
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cimetidine-sulfoxide.html
Purity
97.0
Solubility
DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=S(CC/N=C(NC)/NC#N)CC1=C(C)N=CN1
Molecular Formula
C10H16N6OS
Molecular Weight
268.35
Precautions
H301, H311, H331
References & Citations
[1] Larsson R, et al. The pharmacokinetics of cimetidine and its sulphoxide metabolite in patients with normal and impaired renal function. Br J Clin Pharmacol. 1982;13 (2) :163-170.|[2]HE Barber, et al. The Transport of Cimetidine Across the Rat Small Intestine in Vitro. B r J Pharmacol. 1979 Jul;66 (3) :496P-497P.|[3] Ryta A. Kuzel, et al. Investigations into the chirality of the metabolic sulfoxidation of cimetidine. Chirality (1994), 6 (8), 607-14.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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