TFAP

• UNSPSC Description:

  TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 μM.

• Target Antigen:

  COX; Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation;Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/TFAP.html

• Purity:

  99.98

• Solubility:

  DMSO : ≥ 155 mg/mL

• Smiles:

  O=C(NC1=NC=C(N)C=C1)C2=CC=C(C(F)(F)F)C=C2

• Molecular Weight:

  281.23

• References & Citations:

  [1]Kakuta H, et al. Identification of urine metabolites of TFAP, a cyclooxygenase-1 inhibitor. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1840-3.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1011244-68-0