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Carbosulfan

CAT: 0804-HY-B2015-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B2015-01Size:100 mg
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Description
Carbosulfan inhibited relatively potently CYP3A4 and moderately CYP1A1/2 and CYP2C19 in pooled HLM (human livers) . Carbosulfan activation is predominantly catalyzed in humans by CYP3A4.
CAS Number
55285-14-8
UNSPSC
12352005
Hazard Statement
H301, H317, H330, H410
Target
Cytochrome P450; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Carbosulfan.html
Concentration
10mM
Purity
98.0
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(OC1=C(OC(C)(C)C2)C2=CC=C1)N(SN(CCCC)CCCC)C
Molecular Formula
C20H32N2O3S
Molecular Weight
380.54
Precautions
H301, H317, H330, H410
References & Citations
[1]Abass K, et al. Metabolism of carbosulfan II. Human interindividual variability in its in vitro hepatic biotransformation and the identification of the cytochrome P450 isoforms involved. Chem Biol Interact. 2010 May 14;185 (3) :163-173.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CYP1; CYP2; CYP3

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