SBE-β-CD

• Description:

  SBE-β-CD is a sulfobutylether β-cyclodextrin derivative used as an excipient or a formulating agent to increase the solubility of poorly soluble agents[1].

• Product Name Alternative:

  Sulfobutylether-β-Cyclodextrin

• UNSPSC:

  12352200

• Hazard Statement:

  H317

• Target:

  Biochemical Assay Reagents

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/SBE-_beta_-CD.html

• Purity:

  99.89

• Solubility:

  H2O : ≥ 100 mg/mL

• Smiles:

  [R]O[C@@H]1[C@H] (O[R]) [C@H] (O[C@@H]2[C@H] (O[R]) C (O[R]) [C@H] (O3) [C@@H] (CO[R]) O2) [C@@H] (CO[R]) O[C@@H]1O[C@H]4[C@H] (O[R]) [C@@H] (O[R]) [C@@H] (O[C@H]5[C@H] (O[R]) [C@@H] (O[R]) [C@@H] (O[C@@H]6C (O[R]) [C@H] (O[R]) [C@H] (O[C@@H]7[C@@H] (O[R]) [C@H] (O[R]) [C@H] (O[C@@H]8[C@@H] (O[R]) [C@H] (O[R]) [C@H]3O[C@H]8CO[R]) O[C@H]7CO[R]) O[C@H]6CO[R]) O[C@@H]5CO[R]) O[C@@H]4CO[R].[R= H 21-m or C4H8SO3-Na+ m , m=6.0-7.1]

• Molecular Weight:

  2083-2257

• Precautions:

  H317

• References & Citations:

  [1]Fukuda M, et al.Influence of sulfobutyl ether beta-cyclodextrin (Captisol) on the dissolution properties of a poorly soluble drug from extrudates prepared by hot-melt extrusion.Int J Pharm. 2008 Feb 28;350 (1-2) :188-196|[2]Charman SA, et al. Alteration of the intravenous pharmacokinetics of a synthetic ozonide antimalarial in the presence of a modified cyclodextrin. J Pharm Sci. 2006 Feb;95 (2) :256-67

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  Biochemical Assay Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  182410-00-0