SBE-β-CD

• Description :

  SBE-β-CD is a sulfobutylether β-cyclodextrin derivative used as an excipient or a formulating agent to increase the solubility of poorly soluble agents[1].

• Product Name Alternative :

  Sulfobutylether-β-Cyclodextrin

• UNSPSC :

  12352200

• Hazard Statement :

  H317

• Target :

  Biochemical Assay Reagents

• Type :

  Biochemical Assay Reagents

• Related Pathways :

  Others

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/SBE-_beta_-CD.html

• Purity :

  99.89

• Solubility :

  H2O : ≥ 100 mg/mL

• Smiles :

  [R]O[C@@H]1[C@H](O[R])[C@H](O[C@@H]2[C@H](O[R])C(O[R])[C@H](O3)[C@@H](CO[R])O2)[C@@H](CO[R])O[C@@H]1O[C@H]4[C@H](O[R])[C@@H](O[R])[C@@H](O[C@H]5[C@H](O[R])[C@@H](O[R])[C@@H](O[C@@H]6C(O[R])[C@H](O[R])[C@H](O[C@@H]7[C@@H](O[R])[C@H](O[R])[C@H](O[C@@H]8[C@@H](O[R])[C@H](O[R])[C@H]3O[C@H]8CO[R])O[C@H]7CO[R])O[C@H]6CO[R])O[C@@H]5CO[R])O[C@@H]4CO[R].[R=H21-morC4H8SO3-Na+m,m=6.0-7.1]

• Molecular Weight :

  2083-2257

• Precautions :

  H317

• References & Citations :

  [1]Fukuda M, et al.Influence of sulfobutyl ether beta-cyclodextrin (Captisol) on the dissolution properties of a poorly soluble drug from extrudates prepared by hot-melt extrusion.Int J Pharm. 2008 Feb 28;350 (1-2) :188-196|[2]Charman SA, et al. Alteration of the intravenous pharmacokinetics of a synthetic ozonide antimalarial in the presence of a modified cyclodextrin. J Pharm Sci. 2006 Feb;95 (2) :256-67

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Biochemical Assay Reagents

• Clinical Information :

  No Development Reported

• CAS Number :

  [182410-00-0]