9-Fluorenol

• Description :

  9-Fluorenol (9-Hydroxyfluorene; compound 3) is a dopamine (DAT) inhibitor with IC50 value of 9 μM. 9-Fluorenol is a major metabolite of compound developed as a wake promoting agent. 9-Fluorenol shows wake promotion activity in vivo[1].

• Product Name Alternative :

  9-Hydroxyfluorene

• UNSPSC :

  12352005

• Hazard Statement :

  H302

• Target :

  Dopamine Receptor; Drug Metabolite

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/9-fluorenol.html

• Purity :

  99.87

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  OC1C2=CC=CC=C2C3=CC=CC=C31

• Molecular Formula :

  C13H10O

• Molecular Weight :

  182.22

• Precautions :

  H302

• References & Citations :

  [1]Dunn D, et al. Wake promoting agents: search for next generation modafinil, lessons learned: part III. Bioorg Med Chem Lett. 2012 Jun 1;22 (11) :3751-3.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1689-64-1]