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Tucidinostat-d4

CAT: 0804-HY-109015SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-109015SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tucidinostat-d4 is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively[1].
Product Name Alternative
Chidamide-d4; HBI-8000-d4; CS 055-d4
UNSPSC
12352005
Target
HDAC; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.63
Solubility
10 mM in DMSO
Smiles
O=C(C1=C([2H])C([2H])=C(CNC(/C=C/C2=CN=CC=C2)=O)C([2H])=C1[2H])NC(C=CC(F)=C3)=C3N
Molecular Formula
C22H15D4FN4O2
Molecular Weight
394.43
References & Citations
[1]Ning ZQ, et al. Chidamide (CS055/HBI-8000) : a new histone deacetylase inhibitor of the benzamide class with antitumor activity and the ability to enhance immune cell-mediated tumor cell cytotoxicity. Cancer Chemother Pharmacol. 2012 Apr;69 (4) :901-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC10; HDAC2; HDAC3

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