FR-A-19

CAT: 0804-HY-123728Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-123728Size:1 Each

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Description

FR-A-19 is a potent histamine H2-agonist with IC50 values of 0.02, 0.015, and 0.008 μM targets arpromidine, BUA-75, and FRA-19 respectively. FR-A-19 has potent anti-allergic properties[1].

CAS Number

141099-46-9

UNSPSC

12352005

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/fr-a-19.html

Smiles

N=C(NCCCC1=CN=CN1)N(CCCC2=CC=C(F)C=C2)CCCC3=CC=C(F)C=C3.[H]Cl.[H]Cl.[H]Cl

Molecular Formula

C25H34Cl3F2N5

Molecular Weight

548.93

References & Citations

[1]J Kleine-Tebbe, et al. Modulation of IgE-mediated histamine release from human leukocytes by a new class of histamine H2-agonists. Agents Actions. 1992 Mar;35 (3-4) :185-91.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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FR-A-19

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