Hydroxy-PEG4- (CH2) 2-Boc

• Description :

  Hydroxy-PEG4- (CH2) 2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Hydroxy-PEG4- (CH2) 2-Boc is extracted from patent WO2004008101A2 (compound 191) . Hydroxy-PEG4- (CH2) 2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs.

• UNSPSC :

  12352203

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  ADC Linker; PROTAC Linkers

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related; PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/hydroxy-peg4-ch2-2-boc.html

• Purity :

  99.34

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(OC(C)(C)C)CCOCCOCCOCCOCCO

• Molecular Formula :

  C15H30O7

• Molecular Weight :

  322.39

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Qingqi Chen, et al. The use of isocyanate linkers to make hydrolyzable active agent biopolymer conjugates. Patent WO2004008101A2.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• Isoform :

  Alkyl/ether Linkers; Non-cleavable Linker; PEG Linkers

• CAS Number :

  [518044-32-1]