DQP-1105
CAT:
804-HY-107711-01
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DQP-1105
- CAS Number: 380560-89-4
- UNSPSC Description: DQP-1105 is a potent noncompetitive NMDA receptor antagonist. DQP-1105 inhibits GluN2C- and GluN2D-containing receptors (IC50=7.0 and 2.7 μM, respectively). The IC50 values are at least 50-fold lower than those for recombinant GluN2A-, GluN2B-, GluA1-, or GluK2-containing receptors[1].
- Target Antigen: iGluR
- Type: Reference compound
- Related Pathways: Membrane Transporter/Ion Channel;Neuronal Signaling
- Applications: Neuroscience-Neurodegeneration
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/dqp-1105.html
- Purity: 98.10
- Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: O=C(CCC(N1N=C(CC1C2=CC=C(C=C2)Br)C3=C(C4=CC=CC=C4)C5=C(C=CC(C)=C5)NC3=O)=O)O
- Molecular Weight: 558.42
- References & Citations: [1]Acker TM, et al. Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators. Mol Pharmacol. 2011;80(5):782-795.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, stored under nitrogen)
- Clinical Information: No Development Reported