Products for Research Use Only
RegisterLogin

DQP-1105

CAT: 0804-HY-107711-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-107711-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DQP-1105 is a potent noncompetitive NMDA receptor antagonist. DQP-1105 inhibits GluN2C- and GluN2D-containing receptors (IC50=7.0 and 2.7 μM, respectively) . The IC50 values are at least 50-fold lower than those for recombinant GluN2A-, GluN2B-, GluA1-, or GluK2-containing receptors[1].
CAS Number
380560-89-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dqp-1105.html
Purity
98.00
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(CCC(N1N=C(CC1C2=CC=C(C=C2)Br)C3=C(C4=CC=CC=C4)C5=C(C=CC(C)=C5)NC3=O)=O)O
Molecular Formula
C29H24BrN3O4
Molecular Weight
558.42
Precautions
H302, H315, H319, H335
References & Citations
[1]Acker TM, et al. Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators. Mol Pharmacol. 2011;80 (5) :782-795.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor

Related Products

CatalogName
HY-155810-01DQP-26
HY-155811-01DQP-997-74
HY-161743-01PBA-1105
HY-P990623-01MDX-1105
HY-D1383LZ-1105
HY-W015764-01T-1105
HY-161743APBA-1105 (TFA)
HY-P991339ZL-1101
HY-W1009348RR-11055
HY-161744PBA-1106

Alternative Products

CatalogName
MBS5757230DQP 1105
MBS3847109-01DQP-1105
A22610-10DQP-1105 10mg
A22610-5DQP-1105 5mg
A22610-100DQP-1105 100mg
A22610-50DQP-1105 50mg
A22610-25DQP-1105 25mg
A22610-2DQP-1105 2mg
217594NMDAR2C/2D Inhibitor, DQP-1105 (DQP-1105, NMDA Antagonist IV)
GTR19230406-01DQP-26

Popular Products