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N-Boc-PEG1-bromide

CAT: 0804-HY-130503-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-130503-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
N-Boc-PEG1-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG1-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
CAS Number
164332-88-1
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-boc-peg1-bromide.html
Purity
97.87
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(OC(C)(C)C)NCCOCCBr
Molecular Formula
C9H18BrNO3
Molecular Weight
268.15
Precautions
H302, H315, H319, H335
References & Citations
[1]Ruben HERRENDORFF, et al. Carbohydrate ligands that bind to antibodies against glycoepitopes of glycosphingolipids. WO2017046172A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers; Cleavable Linker; PEG Linkers