N-(PEG1-OH)-N-Boc-PEG2-propargyl

• UNSPSC Description:

  N-(PEG1-OH)-N-Boc-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(PEG1-OH)-N-Boc-PEG2-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Target Antigen:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/n-peg1-oh-n-boc-peg2-propargyl.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OCCOCCN(CCOCCOCC#C)C(OC(C)(C)C)=O

• Molecular Weight:

  331.40

• References & Citations:

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2100306-85-0