STAT5-IN-2

• Description :

  STAT5-IN-2 is a STAT5 inhibitor, extracted from reference 1, example 17f. STAT5-IN-2 has potent antileukemic effect[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; STAT

• Type :

  Reference compound

• Related Pathways :

  Apoptosis; JAK/STAT Signaling; Stem Cell/Wnt

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/STAT5-IN-2.html

• Purity :

  99.08

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  CC(CCN1CCOC2=CC(C=CN3)=C3C=C2)(C)C4=C1C=CC(C5=CC=CN=C5)=C4

• Molecular Formula :

  C26H27N3O

• Molecular Weight :

  397.51

• References & Citations :

  [1]Ludovic Juen, et al. New Inhibitor Targeting Signal Transducer and Activator of Transcription 5 (STAT5) Signaling in Myeloid Leukemias. J Med Chem. 2017 Jul 27;60 (14) :6119-6136.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  STAT5

• CAS Number :

  [2111834-61-6]