Oleanolic acid

• UNSPSC Description:

  Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities.

• Target Antigen:

  Autophagy; Endogenous Metabolite; HIV; MAP3K

• Type:

  Natural Products

• Related Pathways:

  Anti-infection;Autophagy;MAPK/ERK Pathway;Metabolic Enzyme/Protease

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Oleanolic-Acid.html

• Purity:

  98.0

• Solubility:

  DMF : 45.45 mg/mL (ultrasonic;warming;heat to 60°C)|DMSO : 5 mg/mL (ultrasonic)

• Smiles:

  C[C@]([C@@]1([H])[C@]2(CC[C@@H]3O)C)(CC[C@@]2([H])C3(C)C)[C@@](C4=CC1)(CC[C@]5(C(O)=O)[C@@]4([H])CC(C)(C)CC5)C

• Molecular Weight:

  456.70

• References & Citations:

  [1]Zhao X, et al. Oleanolic acid suppresses the proliferation of lung carcinoma cells by miR-122/Cyclin G1/MEF2D axis. Mol Cell Biochem. 2015 Feb;400(1-2):1-7.|[2]Liu J, et al. Oleanolic acid inhibits proliferation and invasiveness of Kras-transformed cells via autophagy. J Nutr Biochem. 2014 Nov;25(11):1154-60.|[3]Liu J, et al. p38 MAPK signaling mediates mitochondrial apoptosis in cancer cells induced by oleanolic acid. Asian Pac J Cancer Prev. 2014;15(11):4519-25.|[4]Martín R, et al. Oleanolic acid modulates the immune-inflammatory response in mice with experimental autoimmune myocarditis and protects from cardiac injury. Therapeutic implications for the human disease. J Mol Cell Cardiol. 2014 Jul;72:250-62.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  Launched

• CAS Number:

  508-02-1