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Oleanolic acid

CAT: 804-HY-N0156-01Size: 100 mgDry Ice: NoHazardous: No
100 mgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities.
CAS Number
[508-02-1]
Product Name Alternative
Oleanic acid; Caryophyllin
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; Endogenous Metabolite; HIV; MAP3K
Type
Natural Products
Related Pathways
Anti-infection; Autophagy; MAPK/ERK Pathway; Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Oleanolic-Acid.html
Purity
98.0
Solubility
DMF : 45.45 mg/mL (ultrasonic; warming; heat to 60°C) |DMSO : 5 mg/mL (ultrasonic)
Smiles
C[C@]([C@@]1([H])[C@]2(CC[C@@H]3O)C)(CC[C@@]2([H])C3(C)C)[C@@](C4=CC1)(CC[C@]5(C(O)=O)[C@@]4([H])CC(C)(C)CC5)C
Molecular Formula
C30H48O3
Molecular Weight
456.70
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhao X, et al. Oleanolic acid suppresses the proliferation of lung carcinoma cells by miR-122/Cyclin G1/MEF2D axis. Mol Cell Biochem. 2015 Feb;400 (1-2) :1-7.|[2]Liu J, et al. Oleanolic acid inhibits proliferation and invasiveness of Kras-transformed cells via autophagy. J Nutr Biochem. 2014 Nov;25 (11) :1154-60.|[3]Liu J, et al. p38 MAPK signaling mediates mitochondrial apoptosis in cancer cells induced by oleanolic acid. Asian Pac J Cancer Prev. 2014;15 (11) :4519-25.|[4]Martín R, et al. Oleanolic acid modulates the immune-inflammatory response in mice with experimental autoimmune myocarditis and protects from cardiac injury. Therapeutic implications for the human disease. J Mol Cell Cardiol. 2014 Jul;72:250-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
MAP3K5/ASK1

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