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IL-4 Antibody

CAT: 0223-38-328Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-38-328Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant Murine IL-4 is a 13.5 kDa globular protein containing 121 amino acid residues.
CAS Number
9007-83-4
NCBI Gene ID
16189
Swiss Prot
P07750
Accession Number
P07750
Host
Rabbit
Reactivity
Mouse
Immunogen
Produced from sera of rabbits immunized with highly pure Recombinant Murine IL-4. Anti-Murine IL-4-specific antibody was purified by affinity chromatography employing immobilized Murine IL-4 matrix.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies, Antibody Pairs
Field of Research
COVID-19, Apoptosis, Cancer, Other, Cell Cycle, Stem Cell, Immunology
Purification
IL-4-specific antibody was purified by affinity chromatography employing immobilized Murine IL-4 matrix
Concentration
Batch dependent
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.
Symbol
Il4
NCBI Official Name
Interleukin 4
NCBI Organism
Mus musculus
Other Product Names
BCGF, BCDF, B cell stimulating factor (BSF-1)
Tested Applications
ELISA, WB
Protein ID
P07750.1
Physical Properties
Lyophilized

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