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GPR27 agonist-1

CAT: 0804-HY-164814-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-164814-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GPR27 Agonist-1 (compound I) is a selective GPR27 agonist with pEC50 of 6.34[1].
CAS Number
651295-98-6
UNSPSC
12352101
Target
Orphan Nuclear Receptor; Orphan Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gpr27-agonist-1.html
Smiles
O=C(C1=CC=C(C=C1Cl)Cl)NC2=CC=C(S(=O)(NC3=CC=CC=C3)=O)C=C2
Molecular Formula
C19H14Cl2N2O3S
Molecular Weight
421.30
References & Citations
[1]Pillaiyar T, et al. Structure-activity relationships of agonists for the orphan G protein-coupled receptor GPR27. Eur J Med Chem. 2021 Dec 5;225:113777.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

2,4-dichloro-N-[4-(phenylsulfamoyl)phenyl]benzamide
CAS Number651295-98-6
PubChem CID5157334
IUPAC Name2,4-dichloro-N-[4-(phenylsulfamoyl)phenyl]benzamide
Molecular FormulaC19H14Cl2N2O3S
Molecular Weight421.3
XLogP4.5
Topological Polar Surface Area83.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Heavy Atom Count27
Formal Charge0
Complexity597
SMILES
C1=CC=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)C3=C(C=C(C=C3)Cl)Cl
InChI
InChI=1S/C19H14Cl2N2O3S/c20-13-6-11-17(18(21)12-13)19(24)22-14-7-9-16(10-8-14)27(25,26)23-15-4-2-1-3-5-15/h1-12,23H,(H,22,24)
InChIKey
LNUTUGZHBGDTOU-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2,4-dichloro-N-[4-(phenylsulfamoyl)phenyl]benzamide
CAS: 651295-98-6
CID: 5157334
Formula: C19H14Cl2N2O3S
MW: 421.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight421.3
XLogP34.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Exact Mass420.0102189
Monoisotopic Mass420.0102189
Topological Polar Surface Area83.7 Ų
Heavy Atom Count27
Formal Charge0
Complexity597
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
T201309-01GPR27 agonist-1
K7101502Gpr27 sgRNA CRISPR Lentivector (Rat) (Target 1)
K0890202GPR27 sgRNA CRISPR Lentivector (Human) (Target 1)
036239GPR27, ID (GPR27, SREB1, Probable G-protein coupled receptor 27, Super conserved receptor expressed in brain 1)
MBS6303889-01GPR27, ID (GPR27, SREB1, Probable G-protein coupled receptor 27, Super conserved receptor expressed in brain 1) (Biotin)
MBS6303887-01GPR27, ID (GPR27, SREB1, Probable G-protein coupled receptor 27, Super conserved receptor expressed in brain 1) (AP)
MBS6303890-01GPR27, ID (GPR27, SREB1, Probable G-protein coupled receptor 27, Super conserved receptor expressed in brain 1) (FITC)
MBS6303888-01GPR27, ID (GPR27, SREB1, Probable G-protein coupled receptor 27, Super conserved receptor expressed in brain 1) (APC)
MBS6303897-01GPR27, ID (GPR27, SREB1, Probable G-protein coupled receptor 27, Super conserved receptor expressed in brain 1) (PE)
036239-PEGPR27, ID (GPR27, SREB1, Probable G-protein coupled receptor 27, Super conserved receptor expressed in brain 1) (PE) discontinued

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