Products for Research Use Only
RegisterLogin

Tissue Factor Antibody / CD142 / F3

CAT: 0013-GTR18717004Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18717004Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble fibrin clots and the promotion of platelet aggregation. Coagulation Factor V (Factor V, FV, proaccelerin, labile factor) is a 2,196 amino acid, single chain glycoprotein that is cleaved by Thrombin to yield an active, Ca2+-dependent dimer that is essential to the blood coagulation cascade. Together with catalytic Factor Xa and Ca2+ on the surface of platelets or endothelial cells, Factor Va coordinates into a prothrombinase complex, which mediates proteolysis of Prothrombin into active Thrombin. Tissue factor (TF), also designated coagulation Factor III) is a cell surface glycoprotein that enables cells to initiate blood coagulation cascades. It functions as a high-affinity receptor for coagulation Factor VII.
UniProt
P13726
Reactivity
Human
Immunogen
A portion of amino acids 50-250 from human F3 protein was used as the immunogen for the Tissue Factor antibody.
Clonality
Monoclonal
Clone
CD142/9195
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml, Western blot: 2-4ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the Tissue Factor antibody should be determined by the researcher.
Tested Applications
IHC-P, WB
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa

UniProtKB · P13726

Tissue factor

TF_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P13726
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
F3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
TF
EC number
—
Processing
Precursor
Secondary accessions
D3DT47, Q6FHG2, Q86WH4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Blood coagulationHemostasis

PTM

Disulfide bondGlycoproteinLipoproteinPalmitate

Cellular component

MembraneSecreted

Domain

SignalTransmembraneTransmembrane helix

Related Products

CatalogName
GTR18717001F3 Antibody / Tissue Factor / CD142
GTR18224747F3/CD142/Tissue factor Antibody
GTR18717003-01F3 Antibody / Tissue Factor / CD142
GTR18315394F3 / Factor III / Tissue Factor / CD142 Reference Antibody
GTR18311284-01F3 / Factor III / Tissue Factor / CD142 Reference Antibody
GTR18316301F3 / Factor III / Tissue Factor / CD142 Reference Antibody (tisotumab)
GTR18594573-01Tisotumab Biosimilar (F3 / Factor III / Tissue Factor / CD142 Reference Antibody)
GTR18315524F3 / Factor III / Tissue Factor / CD142 Reference Antibody (TNX-832)
GTR18594574-01TNX-832 Biosimilar (F3 / Factor III / Tissue Factor / CD142 Reference Antibody)
GTR18594908-01TF Biosimilar (Chugai patent F3 / Factor III / Tissue Factor / CD142 Reference Antibody)

Alternative Products

CatalogName
100-158a-L100CD142 (Tissue factor)
CST 47769STissue Factor/CD142 Antibody
RQ5414Tissue Factor Antibody / CD142
R32003CD142 Antibody / Tissue Factor
abx141195-01Tissue Factor (CD142) Antibody
V5690-20UGTissue Factor Antibody / CD142 / F3
E21-479CD142/Tissue factor/F3
V5691-100UGF3 Antibody / Tissue Factor / CD142
abx414338Tissue Factor (CD142) Antibody (FITC)
R31962Tissue Factor Antibody / TF / CD142

Popular Products