CCX-777

• UNSPSC Description:

  CCX-777 is a partial agonist of β-arrestin-2 recruitment to ACKR3 (atypical chemokine receptor 3)[1].

• Target Antigen:

  Arrestin

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ccx-777.html

• Purity:

  98.73

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C(NCCN1CCCC1)CC(N2CCN(C3=C4N=CC=CC4=CC=C3OC)CCC2)C5=CSC(N6CCOCC6)=N5

• Molecular Weight:

  593.78

• References & Citations:

  [1]Gustavsson M, et al. Structural basis of ligand interaction with atypical chemokine receptor 3. Nat Commun. 2017 Jan 18;8:14135.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported

• CAS Number:

  1226686-36-7