CCX-777

• Description :

  CCX-777 is a partial agonist of β-arrestin-2 recruitment to ACKR3 (atypical chemokine receptor 3) [1].

• CAS Number :

  [1226686-36-7]

• UNSPSC :

  12352005

• Target :

  Arrestin

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ccx-777.html

• Concentration :

  10mM

• Purity :

  98.73

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  O=C(NCCN1CCCC1)CC(N2CCN(C3=C4N=CC=CC4=CC=C3OC)CCC2)C5=CSC(N6CCOCC6)=N5

• Molecular Formula :

  C31H43N7O3S

• Molecular Weight :

  593.78

• References & Citations :

  [1]Gustavsson M, et al. Structural basis of ligand interaction with atypical chemokine receptor 3. Nat Commun. 2017 Jan 18;8:14135.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported