Products for Research Use Only
RegisterLogin

4-MMPB

CAT: 0804-HY-118480-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-118480-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
4-MMPB is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM. 4-MMPB has IC50s of 19.5 μM and 19.1 μM for soybean 15-lipoxygenase (SLO) and human 15-lipoxygenase-1 (15-LOX-1), respectively. 4-MMPB has potential for the research of prostate cancer[1][2][3][4].
CAS Number
928853-86-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Apoptosis; Lipoxygenase
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/4-mmpb.html
Purity
98.54
Solubility
DMSO : 7.69 mg/mL (ultrasonic)
Smiles
CC1=C2NC3=C(SC2=NC(N4CCN(CC4)C)=N1)C=CC=C3
Molecular Formula
C16H19N5S
Molecular Weight
313.42
Precautions
H302, H315, H319
References & Citations
[1]Mohsen Nikpour, et al. Synthesis of new series of pyrimido[4,5-b][1,4] benzothiazines as 15-lipoxygenase inhibitors and study of their inhibitory mechanism. 2013, 22 (10), 5036-5043.|[2]Seyed Jamal Alavi, et al. A novel class of human 15-LOX-1 inhibitors based on 3-hydroxycoumarin. Chem Biol Drug Des. 2018 Jun;91 (6) :1125-1132.|[3]M Bakavoli, et al. Design and synthesis of pyrimido[4,5-b][1,4]benzothiazine derivatives, as potent 15-lipoxygenase inhibitors. Bioorg Med Chem. 2007 Mar 1;15 (5) :2120-6.|[4]Saffiyeh Saboormaleki, et al. 7-Farnesyloxycoumarin Exerts Anti-cancer Effects on a Prostate Cancer Cell Line by 15-LOX-1 Inhibition. Arch Iran Med. 2018 Jun 1;21 (6) :251-259.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-161707MMP2-IN-4
HY-146217MMP-9-IN-4
HY-168560MMP Inhibitor 4
HY-170604MMP-2 Inhibitor-4
HY-W099255-01Ethyl 4,4,4,4',4',4'-hexafluoro-DL-valinate
HY-W7200064,4'-Diapo-ω, ω-carotene-4,4'-dial
HY-77910-014- (4-Bromophenyl) -4-hydroxypiperidine
HY-W0142264,4'-Dihydroxybenzophenone
HY-N90384',4''-Dihydroxyanigorootin
HY-W011927-014,4'-Sulfonyldiphenol

Alternative Products

CatalogName
GTR19165859-014-MMPB
PC64124,4,4-Trifluorobutyl 4,4,4-trifluorobutanoate
PC52154,4,4,4',4',4'-Hexafluorovaline hydrochloride
OR1011273-014,4',4'',4'''-Methanetetrayltetrabenzaldehyde
OR1011238-014,4,4,4-Silanetetrayltetrabenzaldehyde
OR1011275-014,4',4'',4'''-Methanetetrayltetraphenol
PC4810-014,4,4,4',4',4'-Hexafluoro-DL-valine
PC450233-014,4,4,4',4',4'-Hexafluorovaline, ethyl ester
OR1001790-014,4',4'',4'''-Silanetetrayltetrabenzoic acid
25725310-014,4'-Sulfonyldiphenol (4,4'-Dihydroxydiphenylsulfone)

Popular Products