BAY-805

• Description:

  BAY-805, a chemical probe, is a selective inhibitor of ubiquitin-specific protease USP21. BAY-805 has high selectivity for deubiquitinating enzyme (DUB) targets, kinases, proteases and other common target enzymes[1].

• UNSPSC:

  12352005

• Target:

  Deubiquitinase

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bay-805.html

• Concentration:

  10mM

• Purity:

  99.89

• Solubility:

  DMSO : ≥ 200 mg/mL

• Smiles:

  O=C([C@@H](CC(C)C)NC(C1(C(F)(F)F)CCCCC1)=O)NC2=NN=C(CC3=CC=C(C#N)C=C3)S2

• Molecular Formula:

  C24H28F3N5O2S

• Molecular Weight:

  507.57

• References & Citations:

  [1]Göricke F, et al. Discovery and Characterization of BAY-805, a Potent and Selective Inhibitor of Ubiquitin-Specific Protease USP21. J Med Chem. 2023 Feb 20.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  USP21

• CAS Number:

  [2925481-88-3]