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CALHM1 rabbit pAb

CAT: 0855-ES20805-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES20805-01Size:50 µL
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Background
Calcium homeostasis modulator 1 (CALHM1) Homo sapiens This gene encodes a calcium channel that plays a role in processing of amyloid-beta precursor protein. A polymorphism at this locus has been reported to be associated with susceptibility to late-onset Alzheimer's disease in some populations, but the pathogenicity of this polymorphism is unclear.[provided by RefSeq, Mar 2010]
Description
Calcium homeostasis modulator 1 (CALHM1) Homo sapiens This gene encodes a calcium channel that plays a role in processing of amyloid-beta precursor protein. A polymorphism at this locus has been reported to be associated with susceptibility to late-onset Alzheimer's disease in some populations, but the pathogenicity of this polymorphism is unclear. [provided by RefSeq, Mar 2010],
UniProt
Q8IU99
Swiss Prot
Q8IU99
Reactivity
Human; Rat
Immunogen
Synthetic Peptide of CALHM1 AA range: 204-254
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF
Dilution
WB: 1:500-1000 IHC: 1:200-500
Molecular Weight
40kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
40kD
Fragment
IgG
Subcellular Location
Cell membrane; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein . Colocalizes with HSPA5 at the endoplasmic reticulum (PubMed:18585350) . Localizes to the basolateral membrane of epithelial cells including taste cells (By similarity) . .
Other Product Names
Calcium homeostasis modulator protein 1; Protein FAM26C
Gene ID (Human)
255022