RegisterLogin

IMM-01

CAT: 0804-HY-124808-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-124808-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
IMM-01 is a mammalian Diaphanous (mDia) -related formins agonist that inhibits DID-DAD (diaphanous inhibitory domain-diaphanous autoregulatory domain) binding with an IC50 of 140 nM. IMM-01 acts by disrupting the autoinhibitory bond between the DID and DAD domain and thus activates formins. IMM-01 shows anticancer effects[1].
CAS Number
[218795-74-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Ras
Type
Reference compound
Related Pathways
Apoptosis; GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/imm-01.html
Purity
99.87
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC1=CC=C(/C=N/NC(NC(C)(C)C)=S)C(O)=C1
Molecular Formula
C12H17N3O2S
Molecular Weight
267.35
Precautions
H302, H315, H319, H335
References & Citations
[1]L Leanne Lash, et al. Small-molecule intramimics of formin autoinhibition: a new strategy to target the cytoskeletal remodeling machinery in cancer cells. Cancer Res. 2013 Nov 15;73 (22) :6793-803.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 3

Related Products

CatalogName
HY-121490IMM-02
HY-123357IMM-H004
HY-P991186IMM-20059
HY-141645-01IMM-H007
HY-137464A-01OATD-01
HY-122209DVR-01
HY-106839NKS-01
HY-161768VCC972839:01
HY-155870DL-01
HY-156214-01NICE-01

Alternative Products

CatalogName
MBS3616399-01IMM-01
MBS3613071-01IMM-H007
DHJ30701Research Grade Anti-Human IL38/IL1F10 Antibody (IMM-ONC-01)
A137071Anti-IL38/IL1F10 Antibody (IMM-ONC-01) Biosimilar (Monoclonal, IgG1)
T25530-01IMM-02
T9901A-922-01IMM-20059
T24161-01IMM-H004
T32149-01IMM-03

Popular Products