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IMM-H004

CAT: 0804-HY-123357Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-123357Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IMM-H004, a coumarin derivative, possesses neuroprotective and potent free radical scavenging abilities. IMM-H004 significantly inhibits amyloid-β (Aβ) -induced cytotoxicity and apoptosis, offering potential value for research into neurodegenerative diseases such as Alzheimer's disease. Additionally, IMM-H004 is also capable of effectively blocking the calcium mobilization and chemotaxis induced by CKLF1-C27 , thereby alleviating asthmatic pathological changes in the lung tissue of CKLF1 transgenic mice[1].
CAS Number
1456807-80-9
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/imm-h004.html
Smiles
O=C1OC2=C(C(C)=C1N3CCN(CC3)C)C(OC)=CC(O)=C2
Molecular Formula
C16H20N2O4
Molecular Weight
304.34
References & Citations
[1]Song X Y, et al. IMM-H004, a novel coumarin derivative compound, protects against amyloid beta-induced neurotoxicity through a mitochondrial-dependent pathway[J]. Neuroscience, 2013, 242: 28-38.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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