DEX-maleimide

CAT: 0804-HY-46225-01Size: 10 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-46225-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

DEX-maleimide is a coupling agent that can be used to synthesize conjugates containing single-domain antibodies (VHH) conjugated with antigens and anti-inflammatory agents. DEX-maleimide can be used for research on autoimmune diseases[1].

CAS Number

2754462-35-4

UNSPSC

12352005

Target

Drug Intermediate

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/dex-maleimide.html

Purity

99.80

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@]([C@](O)1/C(CO)=N/NC(CCN(C2=O)C(C=C2)=O)=O)(C[C@@H]3O)[C@](C[C@H]1C)([H])[C@@](CCC4=CC5=O)([H])[C@]3([C@]4(C=C5)C)F

Molecular Formula

C29H36FN3O7

Molecular Weight

557.61

References & Citations

[1]Pishesha, et al. Nanobody (VHH) conjugates and uses thereof. U.S., WO2021247688 A2. 2023-07-27.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Chemical Information

DEX-maleimide

CAS Number	2754462-35-4
PubChem CID	170836235
IUPAC Name	3-(2,5-dioxopyrrol-1-yl)-N-[(E)-[1-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-hydroxyethylidene]amino]propanamide
Molecular Formula	C29H36FN3O7
Molecular Weight	557.6
XLogP	0.9
Topological Polar Surface Area	157
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	6
Heavy Atom Count	40
Formal Charge	0
Complexity	1270

SMILES

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(/C(=N/NC(=O)CCN5C(=O)C=CC5=O)/CO)O)C)O)F)C

InChI

InChI=1S/C29H36FN3O7/c1-16-12-20-19-5-4-17-13-18(35)8-10-26(17,2)28(19,30)22(36)14-27(20,3)29(16,40)21(15-34)31-32-23(37)9-11-33-24(38)6-7-25(33)39/h6-8,10,13,16,19-20,22,34,36,40H,4-5,9,11-12,14-15H2,1-3H3,(H,32,37)/b31-21+/t16-,19+,20+,22+,26+,27+,28+,29+/m1/s1

InChIKey

PBGDVXWMHIXDSY-LQKDZXDDSA-N

Chemical Structure

2D Structure

CAS: 2754462-35-4

CID: 170836235

Formula: C29H36FN3O7

MW: 557.6

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	557.6
XLogP3	0.9
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	6
Exact Mass	557.25372866
Monoisotopic Mass	557.25372866
Topological Polar Surface Area	157 Å²
Heavy Atom Count	40
Formal Charge	0
Complexity	1270
Isotope Atom Count	0
Defined Atom Stereocenter Count	8
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
HY-167845-01	LD03-DEX
HY-D2421	DEAE-dex-Cy5
HY-W007324-01	Maleimide
HY-P11268	Tismanitin maleimide
HY-D2932	BG-Maleimide
HY-W591975	Alkyne maleimide
HY-136104-01	Methyltetrazine-Maleimide
HY-W087027-01	Maleimide-NOTA
HY-D1744-01	ICG Maleimide
HY-W998680-01	Fluorescein-maleimide

Alternative Products

Catalog	Name
GTR18183692	DEX Antibody
GTR19241013-01	LD03-DEX
MED1178	Sab Dex with Chloramphenicol
ANT-35321-100ug	DEX/Dextran Antibody
GTR19340213-01	DEAE-dex-Cy5
MED1112	Sab Dex & Chloramphenicol
GTR18183834	DEX Antibody (Biotin)
GTR18183809	DEX Antibody (HRP)
GTR17963387	Dex-1 Antibody
abx085029-01	Maleimide-PEG-Maleimide

DEX-maleimide

Chemical Information

Related Products

Alternative Products

Popular Products