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XEDAR protein

CAT: 0209-101-M861Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-101-M861Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tumor necrosis factor receptor superfamily member 27 is a protein that in humans is encoded by the EDA2R gene. EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support.
Synonyms
Ectodysplasin A2 receptor, EDA2R, EDA-A2 receptor, tumor necrosis factor receptor superfamily member XEDAR, X-linked ectodysplasin-A2 receptor
NCBI Gene ID
60401
UniProt
Q9HAV5
Accession Number
NP_001186616.1
Accession Number mRNA
NM_001199687.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant XEDAR protein
Clone
(#2L23)
Applications
WB, N/B
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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