VAP-1

• Description:

  VAP-1 is a type II membrane cell adhesion protein belonging to the copper/topaquinone oxidase family. It is primarily expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. VAP-1 can catalyze the oxidative deamination of low molecular weight amines, and plays an important role in the migration of lymphocytes to inflamed tissue. Inhibition of VAP-1 can protect against inflammation-related damage to certain injured tissues. Additionally, VAP-1 can function as a significant prognostic marker for certain cancers and cardiovascular diseases.

• Synonyms:

  AOC3; HPAO; SSAO; VAP1; VAP-1

• NCBI Gene ID:

  8639

• UniProt:

  Q16853

• Accession Number:

  NP_003725.1

• Accession Number mRNA:

  NM_003734.3

• Chromosomal Location:

  17q21.31

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  E.coli derived Recombinant Human VAP-1 (#100-141)

• Clone:

  Rabbit IgG

• Applications:

  WB, ELISA

• Purification Method:

  Antigen-affinity purified

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

• Form:

  Lyophilized

• Reconstitution:

  Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

• Storage Conditions:

  The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.

• Host or Source:

  Rabbit

• Isotype:

  Rabbit IgG