VAP-1-IN-3

• UNSPSC Description:

  VAP-1-IN-3 (compound 136) is a potent amine oxidase vascular adhesion protein-1 (VAP-1) inhibitor, with an IC50 of 0.13 μM for VAP-1 isolated from bovine plasma. VAP-1-IN-3 can be used for the research of inflammatory[1].

• Target Antigen:

  VAP-1

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/vap-1-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N#CC1=CC=C(C=C1)C2=NN(N=N2)CC3=CC=CC(CNC(CN)=O)=C3.Cl

• Molecular Weight:

  383.83

• References & Citations:

  [1]Pöstges T, et, al. ω-(5-Phenyl-2H-tetrazol-2-yl)alkyl-substituted glycine amides and related compounds as inhibitors of the amine oxidase vascular adhesion protein-1 (VAP-1). Bioorg Med Chem. 2024 Jan 15:98:117558.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported