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Tryptase-beta

CAT: 0209-103-M498Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-103-M498Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase beta-1, also known as mast cell protease 7 (MCPT7), exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of a diverse array of protease inhibitors in plasma. Tryptase epsilon, also known as brain-specific serine protease 4 (BSSP-4) and brain serine protease 2 (BSP-2), is encoded by the PRSS22 gene and preferentially expressed in epithelium-rich tissues such as lung and eye. Tryptase gamma-1, also called transmembrane tryptase, is encoded by TPSG1, one of many serine protease genes clustered on human chromosome 16p13.3.
Synonyms
Tpsb2; Mcp6; Mcp-6; Mcpt6; MMCP-6; AV011504
NCBI Gene ID
17229
UniProt
Q02844
Accession Number
NP_112464.4
Accession Number mRNA
NM_031187.4
Chromosomal Location
17 A3.3; 17 10.39 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Mouse recombinant protein Tryptase-beta
Clone
(#10H34)
Applications
WB
Purification Method
Protein A/G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

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Alternative Products

CatalogName
365424TPSb2 (Tryptase Beta 2, TPS2, Tryptase Beta II, Tryptase Beta III)
365423TPSb2 (Tryptase Beta 2, TPS2, Tryptase Beta II, Tryptase Beta III)
142648Tryptase (TPS, TPSAB1, Tryptase Alpha/Beta 1, Tryptase Alpha II, Tryptase Beta I, Tryptase-I, Tryptase-II, Tryptase-III)
142649Tryptase (TPS, TPSAB1, Tryptase Alpha/Beta 1, Tryptase Alpha II, Tryptase Beta I, Tryptase-I, Tryptase-II, Tryptase-III)
338322-01Tryptase beta-2
338323-01Tryptase beta-2
AP89178Tryptase beta-2
AP88809Tryptase beta-2
AP78463-01Tryptase beta-2
MBS2888624Tryptase beta-2

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