TNFSF18

• Description:

  Tumor necrosis factor ligand superfamily member 18 is a protein that in humans is encoded by the TNFSF18 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.

• Synonyms:

  Activation-inducible TNF-related ligand, GITR Ligand, GITRL, Glucocorticoid-induced TNF-related ligand, TNFSF18, tumor necrosis factor (ligand) superfamily member 18

• NCBI Gene ID:

  240873

• UniProt:

  Q7TS55

• Accession Number:

  NP_899247.3

• Accession Number mRNA:

  NM_183391.3

• Reactivity:

  Anti-Mouse

• Cross Reactivity:

  Mouse

• Target Antigen:

  Mouse recombinant protein TNFSF18

• Clone:

  (#12D23)

• Applications:

  E, N/B

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Rat

• Isotype:

  IgG2