RegisterLogin

TNFSF11 beta

CAT: 0209-103-M560Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-103-M560Size:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
RANKL ("Receptor Activator of NF-κB Ligand") is a protein of the tumor necrosis factor (TNF) family discovered in 1997 that is significantly involved in the regulation of bone remodeling. The protein is also known as TRANCE (TNF-related activation-induced cytokine), CD254, OPGL, and ODF. RANKL is secreted by, among others, osteoblasts (cells that build bone substance) and binds to the "matching" receptor RANK of monocytic osteoclast progenitor cells, inducing their differentiation into osteoclasts (cells that degrade bone substance again) . The RANK/RANKL system is a biochemical regulatory circuit that causes bone resorption to remain in healthy balance with bone formation, which is a prerequisite for the dynamic architecture of the bone system. This system can be disturbed in various diseases and is therefore of practical interest to medicine. Translated with www.DeepL.com/Translator (free version)
Synonyms
Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor (ODF) ; Osteoprotegerin ligand (OPGL), Receptor activator of nuclear factor kappa-B ligand (RANKL), TNF-related activation-induced cytokine (TRANCE)
NCBI Gene ID
21943
UniProt
O35235
Accession Number
NP_035743.2
Accession Number mRNA
NM_011613.3
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Mouse recombinant protein TNFSF11
Clone
(#7F37)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

Related Products

CatalogName
101-M842TNFSF11 (TRANCE)
101-M672TNFSF11 (TRANCE)
103-M561TNFSF13B beta
103-M494TNFSF1B (TNF-beta)
101-M679TNFSF1B (TNF-beta)
101-M848TNFSF1B (TNF-beta)
103-M495TNFSF6 beta
M60-184-L20RANKL / OPGL / TNFSF11 / CD254 Protein (Fc Tag)
M60-184-L50RANKL / OPGL / TNFSF11 / CD254 Protein (Fc Tag)
101-M680TNFSF3 (Lymphotoxin beta)

Alternative Products

CatalogName
MBS692718-01TNFSF11 beta
529175-01TNFSF11
YP-W16829-01Human TNFSF11 (TNFSF11) ELISA Kit
YP-W35177-01Rat TNFSF11 (TNFSF11) ELISA Kit
MBS8510805-01TNFSF11 Antibody
579601-01Tnfsf11 (HRP)
579600-01TNFSF11 (FITC)
LS-RMAbt-113MRNA-TNFSF11
551575TNFSF11/OPGL

Popular Products