TNFSF6 (Fas Ligand, CD95L)

• Description:

  Fas Ligand is a 40 kDa type II transmembrane protein belonging to the TNF superfamily. The specific receptor for Fas Ligand is Fas (CD95, Apo-1) . Fas Ligand is predominantly expressed on activated T cells and natural killer cells, while Fas is expressed on various types of cells. The Fas/Fas Ligand system plays a crucial role in modulating immune responses by inducing cell specific apoptosis. Human Fas Ligand shares 81% sequence identity with mouse Fas Ligand and 78% sequence identity with rat Fas Ligand.

• Synonyms:

  FASLG; FASL; CD178; CD95L; CD95-L; TNFSF6; APT1LG1

• NCBI Gene ID:

  356

• UniProt:

  P48023

• Accession Number:

  NP_000630.1

• Accession Number mRNA:

  NM_000639.1

• Chromosomal Location:

  1q23

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Human recombinant TNFSF6 (Fas Ligand) EC domain

• Clone:

  (#1E24)

• Applications:

  N, Capture AB

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG2