TNFRSF3

• Description:

  Lymphotoxin beta receptor (LT beta R), also known as TNF C receptor and TNF R2rp, was originally identified as a transcribed sequence with homology to the TNF receptor superfamily. The cytoplasmic region of LT beta R shares little sequence similarity with other TNF receptor family members, suggesting that different signaling mechanisms may be utilized. LT beta R is expressed in a variety of tissues including visceral and lymphoid tissues. The human and mouse LT beta R share 76% amino acid sequence identity.

• Synonyms:

  LTBR; CD18; TNFCR; D12S370; TNFR-RP; TNFRSF3; TNFR2-RP; LT-BETA-R; TNF-R-III

• NCBI Gene ID:

  4055

• UniProt:

  P36941

• Accession Number:

  NP_002333.1

• Accession Number mRNA:

  NM_002342

• Chromosomal Location:

  8q24

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant human TNFRSF3 EC domain

• Clone:

  (#3T24)

• Applications:

  WB, FC

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG1