TNFRSF9

• Description:

  4-1BB is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is alternatively known as TNFRSF9, CD137, and ILA. The human and mouse proteins share 60% amino acid sequence identity. 4-1BB is absent from naive T cells, but it is upregulated and continually expressed following T cell activation.

• Synonyms:

  Tnfrsf9; ILA; Ly63; 4-1BB; Cd137; CDw137; AA408498; AI325004; A930040I11Rik

• NCBI Gene ID:

  21942

• UniProt:

  P20334

• Accession Number:

  NP_035742.1

• Accession Number mRNA:

  NM_011612.2

• Chromosomal Location:

  4 E2; 4 75.5 cM

• Reactivity:

  Anti-Mouse

• Cross Reactivity:

  Mouse

• Target Antigen:

  Mouse recombinant 4-1BB EC-domain

• Clone:

  (#4G33)

• Applications:

  FC, WB

• Purification Method:

  Protein A/G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Rat

• Isotype:

  IgG2