TNF-alpha

CAT: 0209-103-PA09SSize: 100 µgDry Ice: NoHazardous: No
CAT#:0209-103-PA09SSize:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
TNF-α is a pleiotropic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-α is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-α also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. Recombinant murine TNF-α is a soluble 156 amino acid protein (17.3 kDa) which corresponds to C-terminal extracellular domain of the full length transmembrane protein.
Synonyms
Tnf; DIF; Tnfa; TNFSF2; Tnfsf1a; TNFalpha; TNF-alpha
NCBI Gene ID
21926
UniProt
P06804
Accession Number
NP_038721.1
Accession Number mRNA
NM_013693.2
Chromosomal Location
17 B1; 17 19.06 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse TNF-alpha
Clone
Rabbit IgG
Applications
WB
Purification Method
Protein A purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Bioactivity
Western Blot: use at 2-5 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
Host or Source
Rabbit

Related Products

CatalogName
600-179-L100TNF-beta / TNFSF1 / Lymphotoxin alpha Protein
600-179-L1000TNF-beta / TNFSF1 / Lymphotoxin alpha Protein
600-179-L20TNF-beta / TNFSF1 / Lymphotoxin alpha Protein
100-108-L500TNF-beta
100-108-L1000TNF-beta
100-108-L250TNF-beta
100-108-L50TNF-beta
100-108STNF-beta
100-108-L100TNF-beta
102-P88TNF-beta

Alternative Products

CatalogName
TS406983P5TNF alpha (TNF) CytoSection
PR27146-01TNF-alpha
MBS8564081-01TNF alpha

Popular Products