TIE-2, agonistic

• Description:

  Tie-2 is an endothelial-specific receptor tyrosine kinase and a receptor for angiopoietins. Tie-2 is predominantly expressed in the endothelium and it is likely involved in the regulation of vascular maturation and stability.

• Synonyms:

  Angiopoietin-1 receptor; Endothelial tyrosine kinase; HYK; STK1; Tunica interna endothelial cell kinase; Tyrosine kinase with Ig and EGF homology domains-2; Tyrosine-protein kinase receptor TEK; Tyrosine-protein kinase receptor TIE-2; p140 TEK; CD202b; Tek; Hyk; Tie2; AA517024

• NCBI Gene ID:

  21687

• UniProt:

  Q02858

• Accession Number:

  NP_038718.2

• Accession Number mRNA:

  NM_013690.2

• Chromosomal Location:

  4 C5; 4 43.34 cM

• Reactivity:

  Anti-Mouse

• Cross Reactivity:

  Cross reactivity to other species has not been tested!

• Target Antigen:

  Mouse Tie2 extracellular domain

• Clone:

  (#MAB1201)

• Applications:

  WB, Activation

• Purification Method:

  Protein A/G chromatography

• Assay Protocol:

  Centrifuge the vial prior to opening. Reconstitute the antibody with 200 µl sterile PBS and the final concentration is 500 µg/ml.

• Bioactivity:

  WB: 1:500-1000

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS (sterile)

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Rat

• Isotype:

  IgG1