TFF-2

CAT: 0209-M10-243Size: 20 µgDry Ice: NoHazardous: No
CAT#:0209-M10-243Size:20 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute and chronic asthma (Nikolaidis, N.M. et al.sAm. Journal Respir.Cell Mol. Biol.s (2003) 4: 458-464) . Recombinant Murine TFF-2 is an 11.9 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.
Synonyms
Trefoil Factor 2, Spasmolytic Polypeptide (SP), Spasmolysin
NCBI Gene ID
21785
UniProt
Q03404
Accession Number
NP_033389.2
Accession Number mRNA
NM_009363.3
Reactivity
Mouse
Cross Reactivity
Mouse
Sequence
EKPSPCRCSR LTPHNRKNCG FPGITSEQCF DLGCCFDSSV AGVPWCFHPL PNQESEQCVM EVSARKNCGY PGISPEDCAS RNCCFSNLIF EVPWCFFPQS VEDCHY
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Not available!
Length
106
Form
Lyophilized
Molecular Weight
11.2 kDa
Host or Source
E. coli

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