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RELM alpha

CAT: 0209-M10-081Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0209-M10-081Size:25 µg
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Description
RELMα belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELMα and RELMβ are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELMα and Resistin are secreted exclusively by adipocytes while RELMβ is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELMα re still unknown. Recombinant murine RELMα is a 10.0 kDa monomeric protein containing 88 amino acid residues.
Synonyms
Retnla; HIMF; Xcp2; Fizz1; RELMa; Fizz-1; RELMalpha; RELM-alpha; 1810019L16Rik
NCBI Gene ID
57262
UniProt
Q9EP95
Accession Number
NP_065255.2
Accession Number mRNA
NM_020509
Chromosomal Location
16 B5; 16 32.6 cM
Reactivity
Mouse
Cross Reactivity
Mouse, Pig, Intestinal Worm, Parasite
Sequence
MDETIEIIVE NKVKELLANP ANYPSTVTKT LSCTSVKTMN RWASCPAGMT ATGCACGFAC GSWEIQSGDT CNCLCLLVDW TTARCCQLS
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Data not available.
Length
88
Form
Lyophilized
Molecular Weight
10 kDa
Host or Source
E. coli

UniProtKB · Q9EP95

Resistin-like alpha

RETNA_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q9EP95
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Retnla
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q9D8Y4
Protein keywords

PTM

Disulfide bond

Molecular function

Hormone

Technical term

Reference proteome

Cellular component

Secreted

Domain

Signal