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Relaxin-3

CAT: 0209-101-M617Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M617Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Relaxin-3 (H3 relaxin, Insulin-like peptide-7, INSL7) is a secreted protein structurally related to insulin, which is expressed primarily in the brain and central nervous system. Relaxin-3 has been identified as the ligand for the GPCR135 receptor, previously known as “somatostatin-like” or “angiotensin-like” peptide receptor, and also binds specifically to the LGR7 receptor, previously identified as an “orphan” G protein coupled receptor. Signaling by Relaxin-3 through its target receptors is, most likely, part of a CNS processing system, activated in response to signaling by neuropeptides and other factors. Intracerebroventricular injections of Relaxin-3 have been shown to cause a significant increase of food intake and body weight in Wistar rats. Recombinant Relaxin-3 is a 5.5 kDa disulfide linked heterodimeric protein consisting of a 24 amino acid A-chain and a 27 amino acid B-chain.
Synonyms
RLN3; H3; RXN3; ZINS4; insl7
NCBI Gene ID
117579
UniProt
Q8WXF3
Accession Number
NP_543140.1
Accession Number mRNA
NM_080864
Chromosomal Location
19p13.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human Relaxin-3
Clone
(#7G14)
Applications
WB, N
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2