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Prolactin, pegylated

CAT: 0209-500-077Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-500-077Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Prolactin, also known as mammotrophin, luterotropic hormone, and lutetropin, is a neuroendocrine hormone secreted by the pituitary gland. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition, Prolactin plays an immune-regulatory role by stimulating the activities of ornithine decarboxylase and protein kinase C, which are important for the proliferation, differentiation, and function of lymphocytes. Recombinant human Prolactin is a 23 kDa globular protein containing 200 amino acid residues.
Synonyms
Mammotropin, Luterotropic hormone, Lutetropin
NCBI Gene ID
5617
UniProt
P01236
Accession Number
NP_000939.1
Accession Number mRNA
NM_000948
Chromosomal Location
6p22.2-p21.3
Reactivity
Human
Cross Reactivity
Rat, Human
Label
PEG
Sequence
MLPICPGGAA RCQVTLRDLF DRAVVLSHYI HNLSSEMFSE FDKRYTHGRG FITKAINSCH TSSLATPEDK EQAQQMNQKD FLSLIVSILR SWNEPLYHLV TEVRGMQEAP EAILSKAVEI EEQTKRLLEG MELIVSQVHP ETKENEIYPV WSGLPSLQMA DEESRLSAYY NLLHCLRRDS HKIDNYLKLL KCRIIHNNNC
Assay Protocol
It is recommended to reconstitute the lyophilized pegylated hPRL in sterile water or 0.4% NaHCO3 adjusted tp pH 8-9, not less than 100µg/ml, which can then be further diluted to other aqueous solutions, preferably in presence of carrier protein.
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 99% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to induce the proliferation of rat Nb2-11 cells in the concentration range of 0.1-1.0 ng/ml.
Length
200
Form
Lyophilized
Reconstitution
Water
Molecular Weight
23 kDa
Host or Source
E. coli

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