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Oncostatin M

CAT: 0209-102-P76Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-102-P76Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSH can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptor in hepatoma cells. OSM share several structural and functional characteristics with LIF, IL-6, and CNTF. Human OSM is active on murine cells. Recombinant human Oncostatin M is a 26.0 kDa protein, containing 227 amino acid residues.
Synonyms
OSM
NCBI Gene ID
5008
UniProt
P13725
Accession Number
NP_065391.1
Accession Number mRNA
NM_020530.4
Chromosomal Location
22q12.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant Human Oncostatin
Clone
Rabbit IgG
Applications
ELISA, WB, N
Purification Method
Antigen-affinity purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Host or Source
Rabbit

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Alternative Products

CatalogName
O6500-10DOncostatin M (OSM, Oncostatin-M)
216868Oncostatin-M (Oncostatin M, OSM)
130722Oncostatin M (OSM, Oncostatin-M, MGC20461)
O6500-07Oncostatin M (OSM, Oncostatin M Precursor)
O6500-10BOncostatin M (OSM, Oncostatin-MP) discontinued
215757OSM (Oncostatin-M, Oncostatin M) discontinued
AP78389Oncostatin-M
549051Oncostatin M
O6500-10B-APCOncostatin M (OSM, Oncostatin-MP) (APC) discontinued
130724-HRPOncostatin M (OSM, Oncostatin-M, MGC20461) (HRP)

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