Products for Research Use Only
RegisterLogin

NNT-1/BCSF-3

CAT: 0209-100-259SSize: 2 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0209-100-259SSize:2 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NNT-1/BCSF-3 is a neurotrophic factor with B-cell stimulating capabilities. Expressed in lymph nodes and spleen, NNT-1/BCSF-3 binds and activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member beta (LIFR-beta) and induces tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss and B cell hyperplasia associated with increased in serum IgG and IgM. Recombinant human NNT-1/BCSF-3 is a 22.4 kDa protein containing 199 amino acid residues.
Synonyms
CLCF1; CLC; NR6; BSF3; NNT1; BSF-3; CISS2; NNT-1
NCBI Gene ID
23529
UniProt
Q9UBD9
Accession Number
NP_037378.1
Accession Number mRNA
NM_013246
Chromosomal Location
11q13.3
Reactivity
Human
Cross Reactivity
Chicken
Sequence
MLNRTGDPGP GPSIQKTYDL TRYLEHQLRS LAGTYLNYLG PPFNEPDFNP PRLGAETLPR ATVDLEVWRS LNDKLRLTQN YEAYSHLLCY LRGLNRQAAT AELRRSLAHF CTSLQGLLGS IAGVMAALGY PLPQPLPGTE PTWTPGPAHS DFLQKMDDFW LLKELQTWLW RSAKDFNRLK KKMQPPAAAV TLHLGAHGF
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
NT-1/BCSF-3 weakly supports chick E8 DRG neurite outgrowth at a concentration of 1.0 ng/ml.
Length
199
Form
Lyophilized
Molecular Weight
22.4 kDa
Host or Source
E. coli

Related Products

CatalogName
101-M224Chitinase 3-like 1
600-021-L1000CCL14 / HCC-1 / HCC-3 Protein (His Tag)
600-021-L50CCL14 / HCC-1 / HCC-3 Protein (His Tag)
600-230-L50RSPO3 / R-spondin 3 Protein (aa 1-146, His Tag)
600-230-L1000RSPO3 / R-spondin 3 Protein (aa 1-146, His Tag)
600-022-L50CCL14 / HCC-1 / HCC-3 Protein (aa 28-93, His Tag)
M10-015-L50IL-3
100-179-L250GDF-3
100-135-L250BD-3
102-P220BD-3

Alternative Products

CatalogName
HC66630Human NNT-1/BCSF 3
MBS692139-01Human NNT-1/BCSF-3
P1332-10NNT-1/BCSF-3, Human Recombinant
P5675-500μgRecombinant Human NNT-1/BCSF-3
RHF778Anti-Human NNT-1/BCSF-3
PROTQ9UBD9-2Recombinant Human NNT-1/BCSF-3 Protein
RHF778CKHuman NNT-1/BCSF-3 Construction Kit
RHF778BAnti-Human NNT-1/BCSF-3 Biotin
RHF778CKCHuman NNT-1/BCSF-3 Construction Kit w/Developing Reagents
RHF778CKX1Human NNT-1/BCSF-3 "Super-X" Pre-Coated ELISA Kit

Popular Products