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Chitinase 3-like 1

CAT: 0209-101-M224Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M224Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Chitinase-3-like protein 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. The name YKL-40 is derived from the three N-terminal amino acids present on the secreted form and its molecular mass. YKL-40 is expressed and secreted by various cell-types including macrophages, chondrocytes, fibroblast-like synovial cells, vascular smooth muscle cells, and hepatic stellate cells. The biological function of YKL-40 is unclear. It is not known to have a specific receptor. Its pattern of expression is associated with pathogenic processes related to inflammation, extracellular tissue remodeling, fibrosis and solid carcinomas and asthma
Synonyms
39 kDa synovial protein, Cartilage glycoprotein 39 (CGP-39; GP-39; hCGP-39), YKL-40
NCBI Gene ID
1116
UniProt
P36222
Accession Number
NP_001267.2
Accession Number mRNA
NM_001279.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant Chitinase 3-like 1
Clone
(#9X24)
Applications
E
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG1

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