Neuritin Recombinant Protein

Neuritin Recombinant Protein

• Description: Neuritin is a neurotrophic factor, which is expressed in response to induction of neuronal activity by NGF, BDNF, NT3, and other neural stimulators. It is expressed primarily in postmitotic-differentiating neurons of the developing nervous system and in neuronal structures related to synaptic plasticity in the adult nervous system. Neuritin acts as a molecular mediator of neurite outgrowth, neuronal survival, and synaptic maturation. Recombinant human Neuritin is a covalently disulfide-linked homodimer, consisting of two 9.72 kDa polypeptide monomers, each containing 88 amino acid residues.
• Synonyms: CPG15, NRN1
• CAS Number: 9000-83-3
• NCBI Gene ID: 51299
• UniProt: Q9NPD7
• Accession Number: NP_057672.1
• Accession Number mRNA: NM_016588.2
• Gene Location: 6p25.1
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Rat
• Sequence: AGKCDAVFKG FSDCLLKLGD SMANYPQGLD DKTNIKTVCT YWEDFHSCTV TALTDCQEGA KDMWDKLRKE SKNLNIQGSL FELCGSGN
• Detection Range: Determined by a cell proliferation using rat C6 cells. The ED50 for this effect is 20.0-30.0 ng/ml.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 88
• Form: Lyophilized
• Molecular Weight: 9.72 kDa
• Shipping Conditions: Room Temperature