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MMP-10

CAT: 0209-101-M805Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M805Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP10 (stromelysin 2) degrades a broad range of substrates including gelatin, collagen types III, IV and V, fibronectin, aggrecan, and pig cartilage proteoglycan. MMP10 can activate other MMPs such as MMP1 and MMP8. MMP10 is expressed in keratinocytes, T cells, menstrual endometrium and a few tumor samples. Structurally, MMP10 may be divided into four distinct domains: a prodomain which is cleaved upon activation, a catalytic domain containing the zinc binding site; a short linker region, and a carboxyl terminal hemopexin- slike domain.
Synonyms
MMP10; SL-2; STMY2
NCBI Gene ID
4319
UniProt
P09238
Accession Number
NP_002416.1
Accession Number mRNA
NM_002425.2
Chromosomal Location
11q22.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human MMP-10
Clone
(#9G33)
Applications
Detection Ab
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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