MCP-1 (MCAF, CCL2) Recombinant Protein

MCP-1 (MCAF, CCL2) Recombinant Protein

• Description: The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant human MCP-1 is an 8.6 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
• Synonyms: CCL2; HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30
• CAS Number: 9000-83-3
• NCBI Gene ID: 6347
• UniProt: P13500
• Accession Number: NP_002973
• Accession Number mRNA: NM_002982
• Gene Location: 17q11.2-q12
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Chicken, Hamster, Monkey, Mouse, Rat, Human, Leech
• Sequence: QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSMDHLDKQ TQTPKT
• Detection Range: Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 76
• Form: Lyophilized
• Molecular Weight: 8.6 kDa
• Shipping Conditions: Room Temperature