MCP-1 (MCAF, CCL2) Recombinant Protein

• Description:

  The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant human MCP-1 is an 8.6 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

• Synonyms:

  CCL2; HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30

• CAS Number:

  9000-83-3

• NCBI Gene ID:

  6347

• UniProt:

  P13500

• Accession Number:

  NP_002973

• Accession Number mRNA:

  NM_002982

• Gene Location:

  17q11.2-q12

• Host:

  E. coli

• Origin Species:

  Human

• Species Reactivity:

  Chicken, Hamster, Monkey, Mouse, Rat, Human, Leech

• Sequence:

  QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSMDHLDKQ TQTPKT

• Detection Range:

  Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.

• Endotoxin:

  < 0.1 ng/µg of protein (<1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Length:

  76

• Form:

  Lyophilized

• Molecular Weight:

  8.6 kDa

• Shipping Conditions:

  Room Temperature