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LOX-1

CAT: 0209-101-M557Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M557Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lectin-like Oxidized Low-density Lipoprotein Receptor 1 (LOX-1), also known as Oxidized Low-density Lipoprotein Receptor 1 (OLR1), is a type II transmembrane receptor belonging to the class E scavenger receptor (SR-E) subfamily of the C-type lectin family. It binds and supports the internalization of multiple structurally unrelated macromolecules. It exists on the cell surface as covalent homodimers, which can further associate into non-covalently-linked oligomers. Cell surface LOX-1 can also be cleaved to release the soluble LOX-1 extracellular domain.
Synonyms
Olr1; LOX1; LOXIN; SLOX1; CLEC8A; SCARE1
NCBI Gene ID
4973
UniProt
P78380
Accession Number
NP_002534.1
Accession Number mRNA
NM_002543.3
Chromosomal Location
12p13.2-p12.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human LOX-1
Clone
(#1L36)
Applications
WB, N
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1